On my Dev VM, I’ve been unable to manage SQL Server Express with SQL Server Configuration Manager – I get an error “The Remote Procedure call failed”.
The solution: Updates. I found this article:
Which mentions about things breaking wile installing Sql Server 2012 – I didn’t install that, but I did install Visual Studio 2012 – which includes Server Server 2012 components.
Install sql server 2008 sp3, and sql server 2008 r2 sp2. Problems solved.